Finding New Options When Others Haven’t Worked If you’ve tried multiple antidepressants or therapy and still feel stuck, you’re not alone. Treatment-resistant depression (TRD) affects many people and while it can feel frustrating, there are still options that may help you feel better. At Compassionate Psychiatric Services, we specialize in supporting patients with TRD in Frisco and Southlake, TX, offering advanced treatments and integrated care that go beyond the basics. What Is Treatment-Resistant Depression? TRD is generally defined as depression that doesn’t respond to at least two adequate trials of antidepressant medications. This doesn’t mean you’ve failed treatment, it means the treatment hasn’t worked for you, and it’s time for a new approach. Signs You May Have TRD Tried 2 or more antidepressants without sustained improvement Experienced side effects that made treatment hard to continue Continued to feel flat, numb, or hopeless despite treatment Struggled with severe symptoms or suicidal thoughts that persist ow We Treat TRD at Our Frisco and Southlake Clinics We offer advanced, FDA-approved treatments and whole-person support for those with TRD. Your care may include: Spravato® (esketamine): A nasal spray for TRD, given in our REMS-certified clinic under supervision TMS Therapy: A non-invasive option that stimulates specific brain areas involved in mood regulation Medication reassessment: Including possible combination therapy or adjustments Integrated counseling: Therapy alongside medication often leads to better outcomes Telepsychiatry options: For convenient follow-up and continuity of care What Makes Our TRD Treatment Approach Different? We listen carefully and assess thoroughly not just your symptoms, but your full story We believe in choice and collaboration you help shape the plan We offer advanced options in-house, without needing multiple referrals We support you long-term, with providers who understand TRD isn’t one-size-fits-all When to Reach Out If you’ve been told there are “no other options,” or you feel discouraged after trying multiple medications, let’s talk. TRD may require a different path but with the right support, progress is still possible. Call us today to schedule a consultation in Frisco or Southlake, TX. We’re here to help you take the next step with confidence.
